1-METHYL-1H-PYRAZOLE-3-SULFONYL CHLORIDE

1-METHYL-1H-PYRAZOLE-3-SULFONYL CHLORIDE - Names and Identifiers

Name	1-methylpyrazole-3-sulfonyl chloride
Synonyms	LogP 1-Methylpyrazole-3-sulfonyl Chloride 1-methyl-3-pyrazolesulfonyl chloride 1-methylpyrazole-3-sulfonyl chloride 1-METHYL-1H-PYRAZOLE-3-SULFONYL CHLORIDE 1-Methyl-1H-Pyrazole-3-Sulfonyl Chloride 1H-pyrazole-3-sulfonyl chloride, 1-methyl- 1H-Pyrazole-3-sulfonyl chloride, 1-methyl-
CAS	89501-90-6
InChI	InChI=1/C4H5ClN2O2S/c1-7-3-2-4(6-7)10(5,8)9/h2-3H,1H3

1-METHYL-1H-PYRAZOLE-3-SULFONYL CHLORIDE - Physico-chemical Properties

Molecular Formula	C4H5ClN2O2S
Molar Mass	180.61
Density	1.60±0.1 g/cm3(Predicted)
Boling Point	295.7±13.0 °C(Predicted)
Flash Point	132.618°C
Vapor Presure	0.003mmHg at 25°C
pKa	-3.70±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.622

1-METHYL-1H-PYRAZOLE-3-SULFONYL CHLORIDE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs	UN1759

1-METHYL-1H-PYRAZOLE-3-SULFONYL CHLORIDE - Introduction

chloride is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: chloride is a colorless to light yellow liquid.
-Solubility: It has good solubility in common organic solvents.

Use:
-Chemical synthesis: chloride is widely used in chemical synthesis, especially as a reagent or intermediate in organic synthesis reactions. It is often used to introduce a sulfonyl chloride group into the molecule.
-Pharmaceutical field: As a drug intermediate, it plays an important role in the process of preparing drugs.

Preparation Method:
The preparation of the chloride is usually carried out by the following steps:
1. First, 1-methyl pyrazole is reacted with thionyl chloride to generate 1-methyl pyrazole -3-sulfonic acid.
2. Then, the sulfonic acid compound is reacted with phosphorus chloride through a reaction to generate chloride.

Safety Information:
chloride is an irritating compound that may cause irritation and burns in contact with the skin. During use, avoid inhalation of its vapors or contact with skin, eyes and mucous membranes. You should operate in a well-ventilated area and wear personal protective equipment such as protective gloves, protective glasses and protective masks. During storage, it should be kept in a sealed, dry, cool place, away from fire and combustibles. If accidentally touched, should immediately rinse with plenty of water, and medical treatment.

Last Update：2024-04-09 21:01:54